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The heart rate increase often stabilises after the initial adjustment period , though it may persist throughout treatment in some individuals

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MechoulamRBen-ShabatSHanusLLigumskyMKaminskiNESchatzARet al

In another study to investigate the mechanism(s) underlying crocin's vasodilatory effects, isolated rat thoracic aorta rings were contracted by phenylephrine or KCl [75]

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