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SASP IL-6, MMP-1, and MMP-3 are significantly reduced in conditioned media from GHK-Cu-treated senescent HDFs (100 nM, 72h treatment of SA--gal+ passage 22 HDFs), while p16/p21 remain elevated
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Moreover, a possible decrease in CPT-I activity and reduced -oxidationboth of which may contribute to an underlying energy deficit in the study patientsprompted us to assess plasma triglyceride (TG) levels to further explore lipid metabolic disturbances
Tibbetts LS, Shanelec D
A Randomized Controlled Study Comparing the Efficacy of Topical 5% Tranexamic Acid Solution versus 3% Hydroquinone Cream in Melasma
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