Finally, based on the increase in wool and active hair-follicle density in FGF5 KO sheep, we first mapped out the main mechanism of FGF5 function in anagen, including FGF5, FGFR1, androgen, AR, Wnt/-catenin, c-MYC and KRTs, and Shh/GLI2 (Fig
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It is a synthetic version of a protein naturally found in human gastric juices, where its primary role is to heal and protect the gastrointestinal tract
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Benoist 2014, PMID 25187433, retracted 2025 per notice PMID 40312093) is potentiation of hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, driving dendritic spine formation and synaptogenesis via PI3K-AKT
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