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Description

Pharmacological: Natural GLP-1: Secreted 5-30 minutes after meals, returns to baseline within 2 hours Weekly injection: Sustained elevation for 168 hours with gradual decline Microdosing: Intermediate pattern with regular, smaller peaks The Case Against: Significant Drawbacks 1

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Long-term safety and efficacy of the sodium-glucose cotransporter 2 inhibitor, tofogliflozin, added on glucagon-like peptide-1 receptor agonist in Japanese patients with type 2 diabetes mellitus: a 52-week open-label, multicenter, post-marketing clinical study

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