To date, reducing cardiovascular and renal risk in this population was based on strict control of cardiovascular risk factors and the reninangiotensin system blockade
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Figure 5 A meta-analysis of clinical studies indicated that treatment with GLP-1RAs of obese patients with T2MD did not increase the risk of breast tumors, nor did it increase the risk of acute pancreatitis, pancreatic cancer, and overall tumor neoplasia (207209)
Patients with severe renal impairment, a history of pancreatitis, or significant gastrointestinal disease should undergo thorough evaluation before starting retatrutide
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