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However, 'safe' in this context requires careful qualification

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A report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee to revise the 1995 guidelines for the evaluation and management of heart failure)

But its still important to know when things might need attention

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Selenium supplementation demonstrated immunostimulant effects, such as enhanced proliferation of activated T cells, activation of natural killer cells, and tumor cytotoxicity mediated by cytotoxic lymphocytes 5,6