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Accordingly, a different expression of glutathione in the diverse brain areas has been shown in mouse models, where a higher GSH expression may indicate a condition less prone to oxidative stress

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The increasing A aggregation also led to the release of nitric oxide, reactive oxygen species (ROS), and proinflammatory cytokines which are factors that may contribute to neuronal death ( APOE4 difference from other APOE isoforms Apolipoprotein E (APOE) is a protein that transports cholesterol and lipids

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In Individuals with chronic HIV, elevated TNF- concentrations indicate long-term inflammation [15]