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Cells use glutathione to manage oxidative stress, support detoxification pathways, and keep the balance between damage and repair inside the cell

Front Endocrinol (Lausanne) 14:1059228

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Additionally, the authors acknowledge the general positive bias of the published results, the lack of replicative validation studies, and the resulting risk of overestimating treatment efficacy in preclinical models that would provide confidence for the current findings and improve translational significance

Thomas GM, Carbo C, Curtis BR, Martinod K, Mazo IB, Schatzberg D, Cifuni SM, Fuchs TA, von Andrian UH, Hartwig JH, Aster RH, Wagner DD: Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice