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Huang K, Huang L, van Breemen RB

Secondly, ketone bodies are metabolized in mitochondria, resulting in less NAD + consumption and an increase in the NAD + /NADH ratio in the cytoplasm (144)

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

Hyperglycemia decreases G6PD activity through the activation of protein kinase A (PKA) and increase of intracellular oxidative stress, leading to chronic kidney injury, and diabetic kidney disease (DKD) (4345)

Intervention studies have shown that supplementation with riboflavin (the MTHFR cofactor) effectively lowers blood pressure, specifically in individuals with the variant MTHFR 677TT genotype

The Journal of laboratory and clinical medicine