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The most critical factor in dosing frequency is the half-life of the medication

The standard approach is to start tirzepatide at the lowest available dose and increase incrementally every 4 weeks while monitoring gastrointestinal tolerance

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Think Humira-to-Rinvoq: maximize total revenue under the curve, even if it means discounting your lead drug to drive adoption of whats next

Typical daily range: 100300 mcg once daily, raised gradually over an 812 week course