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Finally, the model predicts that p62 knock-down by siSQSTM1 yields lower base levels of Keap1-GFP in the autophagosome and also lower levels upon DEM treatment relative to the siCtrl condition (Fig 3C

5 : 884893 Muller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer PH and Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53

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A separate double-blind, cross-over study also found less air trapping and greater exercise performance in subjects with chronic obstructive pulmonary disease when N -acetylcysteine was administered at a daily 1200-mg dose (304)

PLoS ONE 3 , e3898 (2008)

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