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In this review we will discuss the evidence which suggests renoprotection induced by GLP-1 receptor agonists and the potential mechanisms that may be involved

As a pattern recognition receptor, NLRP6 has been reported to play a role in protecting the host against pathogenic bacteria and viruses

312 These regenerative processes are thought to be partly influenced by GLP-1s regulation of central signaling routes, such as the phosphatidylinositol 3-kinase/protein kinase B pathway, which is crucial for cell survival and proliferation

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