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On December 18, 2023, Structure Therapeutics published the latest clinical data for GSBR-1290 on its official website

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4 Patients with type 2 diabetes who take concomitant glucose-lowering drugs benefit from GLP-1RA independent of Metforin which is commonly used as a first-line medication in the type 2 diabetes patient population

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The long-term goal isn't just to make the lab results look better, to lower the UACR or keep the eGFR from declining, so much as it is to save lives, hearts, and kidneys. Taking medications off-label is not a simple decision to make

The advantage is smaller injection volumes