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It should be taken on a short-term basis and only as directed to avoid potential side effects

Kwizer et al [7] have examined the effects of hepatotoxic drugs such as paracetamol, cocaine, dextropropoxyphene and hycanthone on glutathione content of isolated rat hepatocytes and reported that addition of a hepatotoxic drug caused a rapid fall in glutathione content

A recent meta-analysis indicates a significant increase in seminal AOX and reduction of MDA following AOX therapy although significant inter-study heterogeneity was detected (112)