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Abstract The physiological roles played by the tripeptide glutathione have greatly advanced over the past decades superimposing the research on free radicals, oxidative stress and, more recently, redox signaling

Notably, these studies also established that the mode of administration (IP versus oral) did not influence the radio-mitigative activity of DSePA against RP

Researchers also investigate its function in maintaining protein thiol homeostasis, regulating enzyme activity through protein glutathionylation, and serving as a cofactor for glutathione peroxidase enzymes that neutralize lipid peroxides and hydrogen peroxide