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A meta-analysis of 80 000 patients found GLP-1 RAs were not associated with an increased risk of optic nerve/vision-threatening events [11], and a recent clinical trial of people taking the highest dose of semaglutide demonstrated excellent safety, increased muscle strength and an increased ratio of lean mass relative to total body mass in people taking semaglutide [12]

They should take steps to manage any B12 deficiency that might happen

In human females, blood GSH drops after ovariectomy from 54.69 to 39.29 nmol/L, but is restored by estrogen replacement therapy [1]

Both MDA and SOD levels were normalized per milligram of total protein

Endocrinology, 153, 22082222

11 , S23S32 (1995)