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DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH)

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current research has instead focused on its metabolic degradation and analytical profiling (Rahaman et al

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270,463,464 Here, we focus on elucidating the crucial involvement of zinc in the progression of CVDs, specifically with regard to atherosclerosis (AS), diabetic cardiomyopathy, myocardial ischemia/reperfusion (I/R) injury, and heart events