(2021) employed tandem mass tag proteomics (TMT) and mass spectrometry (MS) to analyze PBMC, identifying differential expression of proteins regulated by the liver X receptor-retinoid X receptor (LXR/RXR) pathway, which modulates lipid metabolism and inflammation, potentially influencing the expression of pro-inflammatory cytokine genes (Schulman, 2017)
Nutrients 10 , 988 (2018)
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Throughout the last two decades, other proteins have become implicated in these pathways, such as MAG and OMGp, although Nogo-A has remained the most relevant in experimental and clinical investigation