After absorption, B12 is bound to transport proteins, 7580% to haptocorrin, which transports B12 in the blood, and 2025% to transcobalamin, which delivers B12 to the tissues, also referred to as active B12 or holo-transcobalamin
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It interacts with the bodys repair mechanisms, supporting regeneration in damaged muscles, tendons, ligaments, and joints
While cyanocobalamin is a common synthetic form used in basic supplements, natural coenzyme forms like methylcobalamin and adenosylcobalamin are often preferred because the body can utilize them immediately for cellular energy and neurological support
L.et al (2018)