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Patients should work with healthcare providers to select an option and to plan monitoring for side effects

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Hormonal effects related to IGF-1 and androgen sensitivity may play a role

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Exendin-4 has been shown to reduce advanced glycation end product (AGE)-induced interleukin (IL)-6 and TNF- production, the expression of receptor for AGE (RAGE), and cell death in mesangial cells (Wang et al., 2014)

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