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Jpn J Clin Pharmacol Ther 1989;20(3):607-618

Patients with thyroid conditions or those on thyroid medications should consult their doctor before use

The top GO molecular functions identified for these genes include oxygen binding, receptor binding, iron-binding, and VEGF receptor binding

Some studies have shown that metformin can reduce the absorption of vitamin B12 in 30% of people with type 2 diabetes (Vitamin B12 deficiency in metformin-treated type-2 diabetes patients, prevalence and association with peripheral neuropathy)

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Also, be careful when it comes to other medications or drinking alcohol while taking the drug