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Discussion This study aimed to investigate whether patients with established schizophrenia would show greater dACC glutamate deficits than recent onset patients, controlling for potential effects of antipsychotic medication exposure, and to elucidate their mechanistic origins and their role in clinical pathogenesis

Clinical trials of semaglutide in non-diabetic adults with obesity showed average weight loss of 10% to 15% of body weight over 68 weeks, independent of blood glucose changes

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HbA1c reductions were clinically meaningful, ranging up to -2.02% at 24 weeks, which was significantly greater than placebo and even dulaglutide in higher dose groups

In plants, under sulfur-limiting conditions they optimize nitrogen assimilation to maintain metabolic homeostasis

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