Westergaard E, Brightman MW
If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)
Escalation protocols mean the dose changes periodically
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This means that every patient (with or without MTHFR) should have a unique treatment plan to navigate them back to optimal health and wellness