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doi: 10.1073/pnas.2100050118 53 FlorosKVChawlaATJohnson-BerroMOKhatriRStamatouliAMBoikosSAet al

This enhanced glutathione shields mitochondria from oxidative damage

By inhibiting NNMT and preserving NAD, 5-Amino-1MQ indirectly boosts SIRT1 activity , leading to: Increased fat oxidation SIRT1 activates PGC-1 (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a master regulator of mitochondrial biogenesis and fat metabolism

Timing can also play a role in how well you feel the effects

Kidneys from NZB/W and age-matched control mice were harvested and analyzed for the presence of the senescence markers

How does this compare to just using a higher dose of retatrutide