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Like ADC, CAR-T cells therapy needs to be very specific because of the risk of off-target that could lead to strong side effects even though expected results should be potentially higher regarding its long-term efficacy

It has been investigated for potential effects on skin pigmentation, based on proposed mechanisms including influence on melanin synthesis pathways

This work remains early-stage and confined to animal and in-vitro studies

Yunger, S

Cloudiness indicates either bacterial contamination or that the peptide has begun to degrade and precipitate out of solution

A phase IB trial of 24-hour intravenous PX-12, a thioredoxin-1 inhibitor, in patients with advanced gastrointestinal cancers