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Krantz MS, Stone CA, Abreo A, Phillips E (2020) Oral challenge with trimethoprim-sulfamethoxazole in patients with sulfa antibiotic allergy

[DOI] [PubMed] [Google Scholar] 34.Peral J.H., Rodrguez S.M., Ayala A.U., Gonzlez-Mesa E., Garcia E.S

Here is a list of some of these complaints: Sinus irritation Fatigue Pain at injection site Nausea Headaches These side effects are likely due to the route of administration, which would typically be a nasal spray or subcutaneously Frequency and Severity of Side Effects Again, data on the side effects related to Selank administration is sparse

This demonstrates that a polymeric nano/microcapsule can shield vitamin C from thermal breakdown and prolong its shelf-life

However, no published RCT has directly compared the combination against either ingredient alone in healthy adults