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For those concerned about overlap, waiting 14 days (two half-lives) reduces circulating semaglutide to approximately 25% of peak levels

PMID 7811344

Patients should review how dose adjustments, lab monitoring, and side effect management are handled before enrolling

doi: 10.1016/S0140-6736(18)32260-8 112 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al

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