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Patterns of cytokine production can set the immune system into one of two dominant modes: T-helper types 1 (Th1) or 2 (Th2)

Native GLP-1 is rapidly cleaved (half-life of 1 to 2 min) by the ubiquitously expressed serine protease dipeptidyl peptidase-4 (DPP-4) and undergoes quick renal elimination [34, 4042]

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