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For specially engineered nanoparticles there are also potential uses for medical diagnosis and therapy at the cellular level, such as to target, highlight and possibly kill cancer cells [192]

Nevertheless, several follow-up studies have reaffirmed DHODHs ferroptosissuppressive function under specific metabolic or oxidativestress conditions 93,94,95,96 , supporting the notion of a contextdependent mechanism rather than a universally essential role

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For context, most GLP-1 medications require consistent use for weeks or months to start working at full therapeutic capacity

Clin Gastroenterol Hepatol (2015) 13:14441449.e1

It is licensed in the UK as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management