2123 The Effect of GLP-1RAs on Systemic Inflammation The ability of GLP-1RAs to reduce systemic inflammation (with decreases in hs-C-reactive protein, TNF-, interleukin-6 and interleukin IL-1) has been demonstrated in animal studies, studies on isolated human tissues and RCTs
Quality of life To measure the health-related quality of life (HRQOL) among our subjects, we used the self-administered life-quality questionnaires, world health organization quality of life-BREF (WHOQOL-BREF), Taiwan version which was well validated with consistency coefficients ranging from 0.70 to 0.77 [14]
GLP-1 is a hormone that the gut produces after eating to regulate blood sugar, slow digestion and manage hunger
doi: 10.1101/gr.849004 58 IrwinDM
After 3 weeks of treatment, mice exhibited a modest though statistically insignificant reduction in total body weight compared with control mice treated with vehicle (saline) (Figure 6A)
Most healthcare providers recommend waiting at least four weeks at each dose before evaluating effectiveness or escalating