Novo Nordisk is limiting the supply of the three lower doses (0.25 mg, 0.5 mg, 1 mg) to US wholesalers for distribution to pharmacies to support patients
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Mechanistic insights from the UNIVERSE study
Hypoglycaemiagenerally defined as blood glucose below 4.0 mmol/Ltriggers a counter-regulatory response involving adrenaline release, which produces symptoms including sweating, tremor, palpitations, and dizziness
Not everyone needs to reach the maximum 15 mg per week
Compounded GLP-1s have not been evaluated by the FDA, but side effects are expected to be similar to other GLP-1-based medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar), flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder)