Therapeutically, pharmacodynamic modeling informs adaptive dosing regimens that outmaneuver resistance development, a dynamic process of adaptation and counter strategy at the molecular level
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Kang J., Kim H.J., Kim T., Lee H., Kim M., Lee S.W., Kim M.S., Koyanagi A., Smith L., Fond G., et al
Mishto, M
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A recent meta-analysis that included 14 studies with 2,046 patients showed that UA levels of patients who had AF recurrence after ablation were significantly higher than in patients who did not have AF recurrence