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2 3 The proposed mechanisms include promotion of angiogenesis (new blood-vessel formation), effects on the nitric-oxide system, and stimulation of fibroblast outgrowth and cell migration through signaling pathways such as FAK-paxillin

Szasz, T., Thakali, K., Fink, G

Despite lack of statistically significant outcome, 42.0% of patients treated with obexelimab (21/50) showed improvement compared to 28.6% on placebo (12/42) (P = 0.183)

However, the effects of prolonged exposure to this medicine on different organ systems and possible cumulative impact require further investigation