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Ethics statement The animal study was approved by Tianjin Medical University General Hospital's Animal Welfare and Ethical Committee (AEWC) in accordance with standard ethical guidelines (Approval Number: IRB2023-DWFL-051)

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PMDD may still be part of the story, but it should not be the automatic answer to every sweaty night

Discussion Just under 20% of recipients discontinued orforglipron during the course of the study but, interestingly, 30% stopped the placebo

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