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Mark Pimentel, MD, Executive Director of the Medically Associated Science and Technology Program at Cedars-Sinai, and a leading expert on microbial overgrowths, puts it this way: Any factor that slows down the speed of flow [of food] through the small intestine has the potential to cause [bacterial] overgrowth. This is important for patients assessing their SIBO risk, because studies suggest GLP-1 signaling can inhibit aspects of the Migrating Motor Complex (MMC)

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Side Effects Comparison# MET-097i Side Effects# Phase 2b data from VESPER trials reported GI adverse events consistent with the GLP-1 class, but detailed rates have not been fully published