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I like it best, the way Lenzi A et al said it in their paper Rationale for Glutathione Therapy published in the Oxford journal Human Reproduction

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Emerging evidence suggests GLP-1 receptor agonists are associated with increased gallstone risk, with clinical trials showing gallbladder disorders in approximately 2.6% of patients on semaglutide versus 1.2% on placebo

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In adults with obesity or overweight and knee osteoarthritis, retatrutide at 12 mg produced 23.7% body weight loss (an average of 60 pounds) compared to 4.6% with placebo over a full treatment period