The more substantial weight reductions of 10-15% of body weight have been observed with higher-dose injectable semaglutide (2.4 mg) used specifically for obesity treatment, not with the Rybelsus formulation
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We identified 7,511 individuals who used GLP-1 RAs and did not undergo dialysis or die within 3 months post-discharge were enrolled as the GLP-1 RAs users group (Table 1)
Both routes demonstrate rapid onset of effects, typically within 30-45 minutes, but the injection tends to produce more intense effects
Whilst GLP-1 medications such as semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda) do not directly target reproductive hormones, the substantial weight loss and metabolic changes they produce can indirectly influence period regularity