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Our nanoBRET findings demonstrate that DA activation of the 2A -adrenergic receptor primarily results in recruitment of G i1 to the receptor with negligible -arrestin2 recruitment while NE treatment causes robust recruitment of both the G protein and -arrestin2

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BDNF plays an important role in neuronal growth, maturation, and survival and it mainly has the following functions (186): (1) increase synaptic plasticity and affect learning and memory