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STEP Trials (Semaglutide Treatment Effect in People with Obesity): STEP trials evaluated semaglutide for weight management in individuals with obesity

This imbalance is hypothesized to contribute to dysfunctions in the reward system, potentially manifesting as anhedonia and other depressive symptoms 45 , a clinical observation that aligns with the psychiatric side effects noted in GLP-1 RAs therapy

C., and Xu R., Associations of Semaglutide With Incidence and Recurrence of Alcohol Use Disorder in RealWorld Population, Nature Communications 15, no

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Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction

Insulin, for example, is commonly recommended because it does not cross the placenta and has been shown to be safe for both the mother and the developing baby