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Dyslipidemia, hyperglycemia, along with other metabolic disorders, results in IR and/or islet cell dysfunction via some shared pathways, such as inflammation, endoplasmic reticulum stress (ERS), oxidative stress, and ectopic lipid deposition

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Both contribute to the normal protection of cells from oxidative stress and the normal function of the immune system

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N-terminal modification of TGF1 by SF