Tuft cells are chemosensory cells detect microbial or parasitic signals and secrete interleukin-25 (IL-25), which activates group 2 innate lymphoid cells (ILC2s) (27)
The signal is real in the data, contested in its meaning, and still unresolved
Thus, we hypothesized that in our in vitro model of DR, normal redox signaling was disrupted by hyperglycemic conditions
Both GLP-1s and GIPs are tied to plenty of other compelling health benefits outside of weight loss, including diabetes management, reduced heart disease risk, and, potentially, dementia prevention
Under conditions of metabolic stress, it migrates to the cell nucleus, where it activates a suite of genes governed by AMPK (AMP-activated protein kinase), the master cellular energy sensor
2023;102:e34755