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Inflammation-associated oral mucosal melanin hyperpigmentation Under circumstances that are not well defined, certain inflammatory cytokines and mediators have the capacity to promote the production of -MSH by oral melanocytes and keratinocytes and to upregulate the expression of MC1R of melanocytes resulting in increased biosynthesis of melanin

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Paradoxical Hair Damage (Overuse): More is not always better

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The original target date of December 1st, 2024 had been delayed, with a new target go live in March 2025