1 H-NMR (400 MHz, DMSO- d6 ): 13.31 (exchangeable proton, 1H) 11.49 (s, 1H), 8.63 (d, J = 5.6 Hz, 1H), 7.85 (d, J = 9.2 Hz, 1H), 7.81 (dd, J = 8.8, 1.1 Hz, 1H), 7.45 (d, J = 8.9 Hz, 1H), 7.437.32 (m, 2 H), 7.28 (d, J = 8.2 Hz, 1H), 7.21 (br s, 1H), 7.04 (t, J = 7.6 Hz, 1H), 6.82 (t, J = 7.4 Hz, 1H), 6.74 (br s, 1H), 2.822.68 (m, 2 H), 2.30 (ddd, J = 16.3, 11.0, 5.0 Hz, 1H), 2.15 (ddd, J = 16.7, 5.2, 5.2 Hz, 1H), 2.00-1.90 (m, 1H), 1.751.62 (m, 1H) ppm
All mice were kept in group housing until the start of the experiment after which they were placed in individual cages containing free access to a running wheel
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392 The relationship of inflammatory response and neurodegenerative disease In the research conducted by Daniel J
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