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These metabolic abnormalities not only interfere with the proliferation, differentiation, and maturation of spermatogonia but also further affect sperm quality and quantity through epigenetic modifications, oxidative stress, and apoptosis [37, 101, 160, 238]

Before prescribing weight loss injections to patients with hypothyroidism, clinicians must conduct comprehensive medical evaluation to ensure safety and appropriateness

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In OSA, studies with first generation GLP-1R agonists (ArGLP-1) and co-agonists (GLP-1/GIP) have demonstrated significant improvements in the apnea-hypopnea index and weight reduction

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