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Finally, combination therapiesincluding GLP-1 receptor agonists paired with agents targeting complementary pathways such as fibroblast growth factor 21 (FGF21) analogues [137]are poised to shape a promising and diverse treatment landscape for MASH

Havent seen it in diabetes, but, obesity rates are are dipping slightly, and, that same time period has associated with it a pretty, significant spike in GLP one utilization across the board

Declaration of generative AI and AI-assisted technologies in the writing process The authors declare that they have not used generative AI (a type of artificial intelligence technology that can produce various types of content including text, imagery, audio and synthetic data

Curr Pharm Des 2011

Considering that PSC activation is a key factor in pancreatic fibrosis, we speculated that excess ROS production induced by high glucose may induce PSC activation in vivo

Mayo Foundation for Medical Education and Research