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Melatonins ability to maintain mitochondrial function may protect against both cuproptosis and ferroptosis, which involve mitochondrial dysfunction [12, 44, 45]

Understanding both the positive experiences and potential challenges articulated by patients helps healthcare providers tailor treatment plans, set realistic expectations, and provide optimal support throughout the weight loss journey

and omega-3 fatty acids, which are associated with slower telomere attrition via anti-inflammatory and antioxidant effects

Lysine lactylation is a recently identified post-translational modification that serves as an intracellular mechanism of lactate sensing and transfer

Figure 8 8.2 Nanoparticle-mediated ferroptosis Nanoparticles (NPs) exhibit outstanding efficacy in precise targeting through both active and passive mechanisms

Following an acute administration of EtOH (5 g/kg, i.p.), KO animals exhibited 30% and 50% less EtOH and AA accumulation in circulation, respectively, suggesting an increased capacity for liver EtOH and AA metabolism in KO mice