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Drug design, development and therapy 9:24852499 Cooke JP, Losordo DW (2015) Modulating the vascular response to limb ischemia: angiogenic and cell therapies
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During the transport process from the intestinal lumen to portal blood, the proportion of butyrate decreased significantly from 21% to 8%, with its concentration further declining sequentially from the portal vein (29 mol/L) to the hepatic vein (12 mol/L) and finally to the peripheral vein (4 mol/L), demonstrating that butyrate uptake was most substantial in the colon, followed by the liver, and then further absorbed in peripheral tissues [1]
Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, Greig NH (2009 Jan 27) GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism