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Despite robust preclinical data for many TCM-derived metabolites, clinical validation remains limited or preliminary for a majority of these compounds

The P5P form is what is used in cellular reactions, and 70-90% of the vitamin B6 circulating in plasma is this active form.[ref] The first step of the B6 conversion process in the liver involves pyridoxal kinase ( PDKX gene)

Additionally, it is straightforward to implement in laboratory settings and is well-suited for clinical diagnostics due to its precision, efficiency, and dependability

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