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Their secondary structure plays a critical role in receptor binding stability, and efficacy, making structural characterization vital for drug development and quality control of these peptides
and 06507 to A.G.G., a Canada Research Chair in Chronic Pain and Related Brain Disorders to Y.D.K., a Chercheur-Boursier Award from the Fonds de recherche en sant du Qubec to A.G.G., a People Program Marie Curie Actions grant of the European Union's Seventh Framework Programme (FP7/2007-2013) to F.F
Underdown MJ
From these results we hypothesize that Dihexa-mediated protection relies, at least in part, on the activation of multiple downstream targets of the HGF/c-Met system (Akt-TOR and Ras-ERK)