Additional insights from the reports include: The most common eligibility requirements used to approve GLP-1 coverage are minimum body mass index (BMI) (90% corporate and 86% multiemployer and public employer), obesity with one other chronic disease (54% and 51%), and participating in a lifestyle modification program (29% and 34%)
Here are its limitations: Mostly animal data
The hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol production, is known to be affected by metabolic status, obesity, and insulin resistance
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R., de Menezes, C., Silva, I